Here are some details.
1. The imposing structure is the Manhattan Municipal Building, built only a few years before the photo was taken. On the right you see the New-York Edison Company, then but one of many neighborhood suppliers of juice, now part of Con-Ed, the city's electric utility.
2. The tower on the left is the Singer Building of 1908, one of the city's first skyscrapers. On right is the Woolworth Building which opened in 1913 and which was, until 1930, the world's tallest building.
3. The tall building with pyramidal roof, at far left, is the Bankers Trust Company Building. Directly to its right is the many-windowed double-rectagle of the Equitable Building. The Singer Building is next and by it is the City Investing Tower.
4. In center, to right of the flag, is the double-topped Park Row Building. To its right is the steeple-topped Temple Court building. Next along, the shiny dome tops the The New York World Building.
5. Unable to string clothes lines across an alleyway, residents are using the pole method to get things dry. I like the variety of window treatments you see in the facade that faces us: distinctive curtains, shades, and awnings. The American flag is a nice touch in this low-income immigrant neighborhood.
6. This is a mystery. The front part is set up to be drawn by a pair or two of horses, but whether it's a single contraption or six parked together I can't tell.
7. Here is the back half of the block, tenements shading the barrows and storefronts.
8. The front half is much the same. If I'm right, the street sign says "Market."
9. Here's our goods wagon with its white horses. Evidently the shop behind belongs to a barber, but is not now open.
I'm pretty sure the location is Monroe and Hamilton Streets, as shown in this extract from an atlas published the year before.
There was no Manhattan Bridge when Will L. Taylor made his panoramic map of Manhattan in 1879. The arrow shows the direction of the camera's lens.
This 1928 aerial view comes from the Fairchild Aerial Surveys Company. I've marked it to show roughly what the camera lens captured.
In 1935, Berenice Abbott placed her camera two blocks west on Henry Street to capture two iconic towers. Though there are obvious differences in vantage and content, this photo is much like our photo. As did the anonymous Detroit Photographic cameraman, she selected a view point which creates a separation between middle distance and far. There's abundant, unseen space between the strongly-lit foreground space and the far-away buildings in hazy light. Both images also have converging diagonals and geometric blocks of dark/light to the right.
Notice that Abbott's shot includes one of two turrets that you can also see in the Manhattan Bridge photo.
Here's another Abbott photo — one of my favorites — which shows the Manhattan end of the span of the Manhattan Bridge. Our unknown photographer place himself on the span to the right, our of our sight, and aimed his camera still further to our right.
A Brief History of Con Edison by ConEd
a re-creation of the living world, a post of Berenice Abbott photos on my blog
Singer Building on nyc-architecture.com
The Woolworth Building on nyc-architecture.com
The Municipal Building on nyc-architecture.com
Park Row Building on nyc-architecture.com
City Investing Tower on nyc-architecture.com
Temple Court on nyc-architecture.com
The New York World Building (also known as the Pulitzer Building) on nyc-architecture.com
Bankers Trust Company Building on nyc-architecture.com
Equitable Building on nyc-architecture.com
Manhattan Bridge on nyc-architecture.com